Research Associate
Fred Hutchinson Cancer Research Center
Contact:
email: dmargine-at-fhcrc.org
Office:
MS D2-190, 1100 Fairview Ave. N., Seattle, WA 98109
tel.: (206) 667-1919 Current research and interests:
Dynamics, function and structure of mitochondria.
Mitochondrial diseases.
Apoptosis.
Mitochondrial proteomics.
Curriculum Vitae: in MS Word format.
Publications:
Margineantu D., Capaldi, R.A. and Marcus, A.H.
(2000). Dynamics
of
the Mitochondrial Reticulum in Live Cells using Fourier
Imaging Correlation Spectroscopy and Digital Video Microscopy.Biophysical Journal, Vol. 79, Issue 4, pp. 1833-1849,
Biophysical Society.
Featured
article.
Gilkerson, R.W., Margineantu,
D., Capaldi, R.A. and Selker, J.M.
(2000). Mitochondrial DNA Depletion Causes
Morphological Changes in the Mitochondrial Reticulum of Cultured Human
Cells, FEBS Letters (Federation of European Biochemical
Societies Letters), Vol. 26, pp. 1-4, Elsevier Science.
Margineantu, D., Brown, R.M., Brown, G.K.,
Marcus, A.H. and Capaldi, R.A. (2002). Heterogeneous
Distribution of Pyruvate Dehydrogenase in the Matrix of Mitochondria,
Mitochondrion. Vol. 1, No. 4, pp. 327-338. Elsevier Science. PDF preprint (5.5Mb file).
Margineantu, D., Cox, W.G., Sherwood, W.,
Beechem, J., Sundell, L., Capaldi, R.A. (2002). Cell Cycle Dependent
Morphology Changes and Associated Mitochondrial DNA Redistribution
in Mitochondria of Human Cell Lines, Mitochondrion. Vol. 1, pp. 425-435. Elsevier Science. MS Word preprint (3.6Mb file). Figure 5 of the paper (4Mb TIF file).
Education:
Ph.D. (Biology), University of Oregon, 2001.
M.D., University of Medicine and Pharmacy Timisoara, Romania, 1996.
